Hygiene in the pharmaceutical sector is a self-evident prerequisite to the quality of pharmaceutical products. Avoiding pathogens transmitted through the air is top priority. A hygienically impeccable and comfortable room climate is essential during development or production processes in the pharmaceutical sector. Air handling systems are, therefore, indispensable for reducing or avoiding airborne pathogens.

AHUs in cleanrooms performs the following basic functions:
• Control airborne particles, dust and micro-organismen-Thru air filtration using high efficiency particulate air (HEPA) filters
• Maintain room pressure (delta p) Areas that must remain cleaner than surrounding areas must be kept under a positive pressurization. Therefore, the AHU must provide more air into the cleaner space than is mechanically removed from that same space.
• Maintain space moisture (relative humidity) Humidity is controlled by cooling air to dew point temperatures or by using desiccant dehumidifiers. Humidity can affect the efficacy and stability of drugs and is sometimes important to effectively mould the tablets.
• Maintain space temperature Temperature can affect production directly or indirectly by fostering the growth of microbial contaminants on workers.
Hygienic Air Handling Units should comply with DIN 1946/4, EN 1751, VDI 6022/1-3, and VDI 3803.